\(3x+y+6z\le5xyz+5xz^2+x^2y+x^2z=x\left(y+z\right)\left(5z+x\right)\)

\(\Rightarrow3x+y+6z\le\frac{1}{2}.2x\left(y+z\right)\left(5z+x\right)\le\frac{1}{54}\left(3x+y+6z\right)^3\)

\(\Rightarrow\left(3x+y+6z\right)^2\ge54\)

\(\Rightarrow3x+y+6z\ge3\sqrt{6}\)

\(\Rightarrow P\ge6\sqrt{6}\)

Áp dụng BĐT Cô - si cho 3 bộ số không âm

\(\Rightarrow\frac{z\left(xy+1\right)^2}{y^2\left(yz+1\right)}+\frac{x\left(yz+1\right)^2}{z^2\left(xz+1\right)}+\frac{y\left(xz+1\right)^2}{x^2\left(xy+1\right)}\ge3\sqrt[3]{\frac{xyz\left(xy+1\right)^2\left(yz+1\right)^2\left(xz+1\right)^2}{x^2y^2z^2\left(yz+1\right)\left(xz+1\right)\left(xy+1\right)}}=3\sqrt[3]{\frac{\left(xy+1\right)\left(yz+1\right)\left(xz+1\right)}{xyz}}\)

Xét \(3\sqrt[3]{\frac{\left(xy+1\right)\left(yz+1\right)\left(xz+1\right)}{xyz}}\)

\(=3\sqrt[3]{\left(\frac{xy+1}{x}\right)\left(\frac{yz+1}{y}\right)\left(\frac{xz+1}{z}\right)}\)

\(=3\sqrt[3]{\left(y+\frac{1}{x}\right)\left(z+\frac{1}{y}\right)\left(x+\frac{1}{z}\right)}\)

Áp dụng BĐT Cô - si

\(\Rightarrow\left\{\begin{matrix}y+\frac{1}{x}\ge2\sqrt{\frac{y}{x}}\\z+\frac{1}{y}\ge2\sqrt{\frac{z}{y}}\\x+\frac{1}{z}\ge2\sqrt{\frac{x}{z}}\end{matrix}\right.\)

\(\Rightarrow\left(y+\frac{1}{x}\right)\left(z+\frac{1}{y}\right)\left(x+\frac{1}{z}\right)\ge8\)

\(\Rightarrow3\sqrt[3]{\left(y+\frac{1}{x}\right)\left(z+\frac{1}{y}\right)\left(x+\frac{1}{z}\right)}\ge3\sqrt[3]{8}\)

\(\Rightarrow3\sqrt[3]{\left(y+\frac{1}{x}\right)\left(z+\frac{1}{y}\right)\left(x+\frac{1}{z}\right)}\ge6\)

\(\Leftrightarrow3\sqrt[3]{\frac{\left(xy+1\right)\left(yz+1\right)\left(xz+1\right)}{xyz}}\ge6\)

Mà \(\frac{z\left(xy+1\right)^2}{y^2\left(yz+1\right)}+\frac{x\left(yz+1\right)^2}{z^2\left(xz+1\right)}+\frac{y\left(xz+1\right)^2}{x^2\left(xy+1\right)}\ge3\sqrt[3]{\frac{\left(xy+1\right)\left(yz+1\right)\left(xz+1\right)}{xyz}}\)

\(\Rightarrow\frac{z\left(xy+1\right)^2}{y^2\left(yz+1\right)}+\frac{x\left(yz+1\right)^2}{z^2\left(xz+1\right)}+\frac{y\left(xz+1\right)^2}{x^2\left(xy+1\right)}\ge6\)

Vậy GTNN của \(\frac{z\left(xy+1\right)^2}{y^2\left(yz+1\right)}+\frac{x\left(yz+1\right)^2}{z^2\left(xz+1\right)}+\frac{y\left(xz+1\right)^2}{x^2\left(xy+1\right)}=6\)

Đặt cái ban đầu là P

Ta có: \(xy+yz+zx=xyz\)

\(\Leftrightarrow\dfrac{1}{x}+\dfrac{1}{y}+\dfrac{1}{z}=1\)

Ta lại có:

\(\dfrac{xy}{z^3\left(1+x\right)\left(1+y\right)}+\dfrac{1+x}{64x}+\dfrac{1+y}{64y}\ge\dfrac{3}{16z}\)

\(\Leftrightarrow\dfrac{xy}{z^3\left(1+x\right)\left(1+y\right)}\ge\dfrac{3}{16z}-\dfrac{1}{32}-\dfrac{1}{64x}-\dfrac{1}{64y}\left(1\right)\)

Tương tự ta có:

\(\left\{{}\begin{matrix}\dfrac{yz}{x^3\left(1+y\right)\left(1+z\right)}\ge\dfrac{3}{16x}-\dfrac{1}{32}-\dfrac{1}{64y}-\dfrac{1}{64z}\left(2\right)\\\dfrac{zx}{y^3\left(1+z\right)\left(1+x\right)}\ge\dfrac{3}{16y}-\dfrac{1}{32}-\dfrac{1}{64z}-\dfrac{1}{64x}\left(3\right)\end{matrix}\right.\)

Từ (1), (2), (3) ta có:

\(P\ge\dfrac{3}{16}\left(\dfrac{1}{x}+\dfrac{1}{y}+\dfrac{1}{z}\right)-\dfrac{1}{32}\left(\dfrac{1}{x}+\dfrac{1}{y}+\dfrac{1}{z}\right)-\dfrac{3}{32}\)

\(=\dfrac{3}{16}-\dfrac{1}{32}-\dfrac{3}{32}=\dfrac{1}{16}\)

Dấu = xảy ra khi \(x=y=z=3\)

Áp dụng Bất Đẳng Thức Cosi ta có \(\hept{\begin{cases}\frac{x^3}{1+y}+\frac{1+y}{4}+\frac{1}{2}\ge3\sqrt[3]{\frac{x^3}{1+y}\cdot\frac{1+y}{4}\cdot\frac{1}{2}}=\frac{3x}{2}\\\frac{y^3}{1+z}+\frac{1+z}{4}+\frac{1}{2}\ge3\sqrt[3]{\frac{y^3}{1+z}\cdot\frac{1+z}{4}\cdot\frac{1}{2}}=\frac{3y}{2}\\\frac{z^3}{1+x}+\frac{1+x}{4}+\frac{1}{2}\ge3\sqrt[3]{\frac{z^3}{1+x}\cdot\frac{1+x}{4}\cdot\frac{1}{2}}=\frac{3z}{2}\end{cases}}\)

Cộng vế theo vế ta được \(P+\frac{3+x+y+z}{4}+\frac{3}{2}\ge\frac{3}{2}\left(x+y+z\right)\)

\(\Leftrightarrow P\ge\frac{5}{4}\left(x+y+z\right)-\frac{9}{4}\)

Mà ta có \(\left(x+y+z\right)^2\ge3\left(xy+yz+zx\right)\ge9\Rightarrow x+y+z\ge3\)

Do đó \(P\ge\frac{5}{4}\cdot3-\frac{9}{4}=\frac{3}{2}\). Dấu "=" xảy ra khi x=y=z=1

Vậy minP=\(\frac{3}{2}\)khi x=y=z=1